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Cul4btm1Swl
Targeted Allele Detail
Summary
Symbol: Cul4btm1Swl
Name: cullin 4B; targeted mutation 1, Shu-Wha Lin
MGI ID: MGI:5438236
Synonyms: Cul4blox
Gene: Cul4b  Location: ChrX:37622151-37665073 bp, - strand  Genetic Position: ChrX, 22.81 cM, cytoband A2
Alliance: Cul4btm1Swl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187403
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 4. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 5. (J:187403)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cul4b Mutation:  37 strains or lines available
References
Original:  J:187403 Chen CY, et al., Rescue of the genetically engineered Cul4b mutant mouse as a potential model for human X-linked mental retardation. Hum Mol Genet. 2012 Oct 1;21(19):4270-85
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory