Ly6g6c^{tm1e(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Ly6g6c^{tm1e(EUCOMM)Hmgu}
• Name: lymphocyte antigen 6 family member G6C; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5433194
• Gene: Ly6g6c Location: Chr17:35286301-35289024 bp, + strand Genetic Position: Chr17, 18.59 cM
• IMPC: Ly6g6c gene page

Mutation origin

• Mutant Cell Lines: HEPD0826_1_A06, HEPD0826_1_A07, HEPD0826_1_B08, HEPD0826_1_C08, HEPD0826_1_D05, HEPD0826_1_D06, HEPD0826_1_D07, HEPD0826_1_E05, HEPD0826_1_E06, HEPD0826_1_E07, HEPD0826_1_G07
• Germline Transmission: Unknown
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The L1L2_Bact_P cassette was inserted at position 35287413 of Chromosome 17 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ly6g6c Mutation: 8 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 1 reference(s)