Tg(FXN*)1Sars
Transgene Detail

Summary

• Symbol: Tg(FXN*)1Sars
• Name: transgene insertion 1, Joseph Sarsero
• MGI ID: MGI:5432794
• Transgene: Tg(FXN*)1Sars Location: Chr5:61912981-61912982 bp Genetic Position: Chr5, Syntenic
• Alliance: Tg(FXN*)1Sars page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(FXN*)1Sars expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FXN (2395)

  Fxn	(MGI:1096879)

  500 GAA trinucleotide repeat inserted

• Mutation details: The transgene contained a bacterial artificial chromosome (BAC) with the entire human frataxin (FXN) gene with a 500 GAA trinucleotide repeat inserted into intron 1. Line 1 contained a single copy of the transgene inserted into chromosome 5. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)