b2b1436Clo
Chemically induced Allele Detail

Summary

• Symbol: b2b1436Clo
• Name: Mutant line 1436; Bench to Bassinet Program (B2B/CVDC), mutation 1436 Cecilia Lo
• MGI ID: MGI:5431500
• Synonyms: Baby Beluga
• Gene: b2b1436Clo Location: unknown
• Alliance: b2b1436Clo page

Mutant 1436-002-LA displays situs inversus totalis

Show the 11 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any b2b1436Clo Mutation: 1 strain or line available

Notes

Summative Diagnosis:
Cardiac defects: Heterotaxy with complex congenital heart diseases such as transposition of the great arteries (TGA) and atrioventricular septal defect (AVSD)
Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
0190	Heterotaxy Syndrome
0700	D-loop transposition of the great arteries
1100	Atrioventricular canal (endocardial cushion defect)
3804	Congenital heart disease

References

• Original: J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12
• All: 2 reference(s)