Tg(Krt15-cre/PGR)1Cot
Transgene Detail

Summary

• Symbol: Tg(Krt15-cre/PGR)1Cot
• Name: transgene insertion 1, George Cotsarelis
• MGI ID: MGI:5428869
• Synonyms: Krt1-15-Cre*PR
• Transgene: Tg(Krt15-cre/PGR)1Cot Location: unknown
• Alliance: Tg(Krt15-cre/PGR)1Cot page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: mifepristone
• Mutation: Insertion
• Tg(Krt15-cre/PGR)1Cot expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Krt15

• Mutation details: The mutated cre/progesterone receptor (Cre*PR; cre/PGR) sequence was cloned into a construct containing the Krt15 (Krt1-15). The purified contruct was injected into fertilized (C57BL/6J x SJL/J)F2 oocytes. (J:146740, J:186301)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Krt15 (species not specified) Summary of all recombinase alleles driven by Krt15.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:146740 Ito M, et al., Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med. 2005 Dec;11(12):1351-4
• All: 2 reference(s)