Smarca1tm1.1Pick
Targeted Allele Detail
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Symbol: |
Smarca1tm1.1Pick |
Name: |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1; targeted mutation 1.1, David J Picketts |
MGI ID: |
MGI:5427348 |
Synonyms: |
Ex6DEL, Snf2l Ex6DEL |
Gene: |
Smarca1 Location: ChrX:46898247-46981490 bp, - strand Genetic Position: ChrX, 25.41 cM, cytoband A3.2
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Alliance: |
Smarca1tm1.1Pick page
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Germline Transmission: |
Earliest citation of germline transmission:
J:183998
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Parent Cell Line: |
J1 (ES Cell)
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Strain of Origin: |
129S4/SvJae
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Allele Type: |
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Targeted (Not Applicable) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A floxed neo cassette was inserted upstream of exon 6 and a loxP site was inserted downstream of exon 6 via homologous recombination. Cre mediated recombination removed the neo cassette and exon 6. The mutant allele produces a stable transcript and a protein product that is 7 kDa smaller than the wild-type protein.
(J:183998)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Smarca1 Mutation: |
12 strains or lines available
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Original: |
J:183998 Yip DJ, et al., Snf2l regulates Foxg1-dependent progenitor cell expansion in the developing brain. Dev Cell. 2012 Apr 17;22(4):871-8 |
All: |
3 reference(s) |
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