Cbln4^tm1Jim
Targeted Allele Detail

Summary

• Symbol: Cbln4^tm1Jim
• Name: cerebellin 4 precursor protein; targeted mutation 1, James I Morgan
• MGI ID: MGI:5426853
• Gene: Cbln4 Location: Chr2:171878256-171885386 bp, - strand Genetic Position: Chr2, 94.74 cM
• Alliance: Cbln4^tm1Jim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184952
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced the coding region. qPCR confirmed the absence of transcript expression in the brain. (J:184952)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cbln4 Mutation: 18 strains or lines available

References

• Original: J:184952 Wei P, et al., The Cbln family of proteins interact with multiple signaling pathways. J Neurochem. 2012 Jun;121(5):717-29
• All: 1 reference(s)