Maged1^tm1Tnab
Targeted Allele Detail

Summary

• Symbol: Maged1^tm1Tnab
• Name: MAGE family member D1; targeted mutation 1, Toshitaka Nabeshima
• MGI ID: MGI:5426784
• Gene: Maged1 Location: ChrX:93579080-93585631 bp, - strand Genetic Position: ChrX, 41.56 cM
• Alliance: Maged1^tm1Tnab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183858
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neo cassette replaced exons 1 through 13. Western blot analysis confirmed the absence of protein expression in brain extracts. (J:183858)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Maged1 Mutation: 9 strains or lines available

References

• Original: J:183858 Mouri A, et al., MAGE-D1 regulates expression of depression-like behavior through serotonin transporter ubiquitylation. J Neurosci. 2012 Mar 28;32(13):4562-80
• All: 1 reference(s)