Smarcal1^tm1Cfbo
Targeted Allele Detail

Summary

• Symbol: Smarcal1^tm1Cfbo
• Name: SNF2 related chromatin remodeling ATPase like 1; targeted mutation 1, Cornelius F Boerkoel
• MGI ID: MGI:5425306
• Synonyms: Smarcal1^loxP
• Gene: Smarcal1 Location: Chr1:72622410-72672293 bp, + strand Genetic Position: Chr1, 36.72 cM
• Alliance: Smarcal1^tm1Cfbo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183899
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. (J:183899)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smarcal1 Mutation: 48 strains or lines available

References

• Original: J:183899 Baradaran-Heravi A, et al., Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression. Hum Mol Genet. 2012 Jun 1;21(11):2572-87
• All: 1 reference(s)