Tg(SNCA)129Mjff
Transgene Detail

Summary

• Symbol: Tg(SNCA)129Mjff
• Name: transgene insertion 129, The Michael J Fox Foundation
• MGI ID: MGI:5424882
• Synonyms: MJFF-9 SNCA WT line 129
• Transgene: Tg(SNCA)129Mjff Location: unknown Genetic Position: Chr7, Syntenic
• Alliance: Tg(SNCA)129Mjff page

Transgene origin

• Strain of Origin: C57BL/6NTac

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intergenic deletion
• Tg(SNCA)129Mjff expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SNCA (6622)

  Snca	(MGI:1277151)

• Mutation details: The human bacterial artificial chromosome (BAC) RP1-458H10, containing the entire synuclein, alpha (non A4 component of amyloid precursor), SNCA, gene was used as the source for the SNCA-Wt transgene, which was linearized and microinjected into the pronucleus of C57BL/6NTac fertilized eggs. Transgene insertion occurred on Chr 7, causing a 898 bp deletion.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)