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Tg(Myh6-MYPN*Y20C)#Jato
Transgene Detail
Summary
Symbol: Tg(Myh6-MYPN*Y20C)#Jato
Name: transgene insertion, Jeffrey A Towbin
MGI ID: MGI:5319508
Synonyms: MYPNY20C
Transgene: Tg(Myh6-MYPN*Y20C)#Jato  Location: unknown  
Alliance: Tg(Myh6-MYPN*Y20C)#Jato page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-MYPN*Y20C)#Jato expresses 1 gene
 
Mutation detailsThis transgene expresses the human MYPN cDNA containing a Y20C mutation under the control of the mouse alpha myosin heavy chain promoter resulting in cardiac-restricted overexpression of the transgene. Two founders were made, however line numbers are not specified. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:181871)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:181871 Purevjav E, et al., Molecular basis for clinical heterogeneity in inherited cardiomyopathies due to myopalladin mutations. Hum Mol Genet. 2012 May 1;21(9):2039-53
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory