Cul7tm2.1Jdec
Targeted Allele Detail
|
Symbol: |
Cul7tm2.1Jdec |
Name: |
cullin 7; targeted mutation 2.1, |
MGI ID: |
MGI:5318992 |
Synonyms: |
p1852loxP |
Gene: |
Cul7 Location: Chr17:46961264-46975290 bp, + strand Genetic Position: Chr17, 22.9 cM
|
Alliance: |
Cul7tm2.1Jdec page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:85161
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
129
|
|
Allele Type: |
|
Targeted (Conditional ready, No functional change) |
Mutation: |
|
Insertion
|
|
|
Mutation details: A targeting vector containing a FRT site flanked NEO cassette and a loxP site was utilized in the construction of this mutant. This selection cassette was inserted upstream of exon 2 of the targeted gene, and another loxP site was inserted downstream of exon 4. Properly targeted mice were crossed to mice expressing FLP recombinase to remove the FRT site flanked neo selection cassette.
(J:85161)
|
|
|
|
Original: |
J:85161 Arai T, et al., Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9855-60 |
All: |
3 reference(s) |
|