Tg(Zfp423-EGFP)7Brsp
Transgene Detail

Summary

• Symbol: Tg(Zfp423-EGFP)7Brsp
• Name: transgene insertion 7, Bruce M Spiegelman
• MGI ID: MGI:5318774
• Synonyms: Zfp423^GFP
• Transgene: Tg(Zfp423-EGFP)7Brsp Location: unknown
• Alliance: Tg(Zfp423-EGFP)7Brsp page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: Coding sequence of EGFP followed by a polyadenylationsignal was inserted into the initiation codon of Zfp423 located in exon 1 from bacterial artificial chromosome RP23-102G4. The modified BAC does not contain any functional domains of Zfp423 or contain full-length coding sequence of any other annotated genes. Five founder lines were produced, two of which were greatly enriched for Zfp423 mRNA in cells positive for EGFP. Data for one of these two lines was published. (J:182285)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:182285 Gupta RK, et al., Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells. Cell Metab. 2012 Feb 8;15(2):230-9
• All: 6 reference(s)