Kcnk1^tm1Barh
Targeted Allele Detail

Summary

• Symbol: Kcnk1^tm1Barh
• Name: potassium channel, subfamily K, member 1; targeted mutation 1, Jacques Barhanin
• MGI ID: MGI:5318212
• Gene: Kcnk1 Location: Chr8:126721909-126757424 bp, + strand Genetic Position: Chr8, 73.67 cM
• Alliance: Kcnk1^tm1Barh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183234
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and a floxed pgk-neo cassette was inserted downstream of exon 2 via homologous recombination. (J:183234)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnk1 Mutation: 28 strains or lines available

References

• Original: J:183234 Nie X, et al., Expression and insights on function of potassium channel TWIK-1 in mouse kidney. Pflugers Arch. 2005 Dec;451(3):479-88
• All: 1 reference(s)