b2b842Clo
Chemically induced Allele Detail

Summary

• Symbol: b2b842Clo
• Name: Mutant line 842; Bench to Bassinet Program (B2B/CVDC), mutation 842 Cecilia Lo
• MGI ID: MGI:5317767
• Gene: b2b842Clo Location: unknown
• Alliance: b2b842Clo page

Mutant 842-006-NB exhibit enlarged atria

Show the 10 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any b2b842Clo Mutation: 1 strain or line available

Notes

Summative Diagnosis:
Cardiovascular defect: Biventricular hypertrophy and muscular (m) ventricular septal defect (VSD)
Noncardiovascular defect: Cleft palate, facial cleft, bilateral kidney agenesis

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
1320	Ventricular septal defect, muscular
3608	Left ventricular hypertrophy
3609	Right ventricular hypertrophy
3804	Congenital heart disease
4503	Agenesis of kidneys
4876	Cleft palate

References

• Original: J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12
• All: 2 reference(s)