Tg(Pcp2-Cbln2)#Jim
Transgene Detail

Summary

• Symbol: Tg(Pcp2-Cbln2)#Jim
• Name: transgene insertion, James I Morgan
• MGI ID: MGI:5316014
• Synonyms: L7-Cbln2
• Transgene: Tg(Pcp2-Cbln2)#Jim Location: unknown
• Alliance: Tg(Pcp2-Cbln2)#Jim page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pcp2-Cbln2)#Jim expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cbln2 (MGI:88282)

• Mutation details: In the transgene construct the mouse cerebellin 2 precursor protein cDNA was inserted into a unique BamHI site in exon 4 of the mouse Purkinje cell protein 2 (L7) gene that had its ATG start site inactivated, thus placing the inserted gene effectively under control of the promoter of the host gene without expressing the host peptide. (J:182277)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:182277 Rong Y, et al., Comparison of Cbln1 and Cbln2 functions using transgenic and knockout mice. J Neurochem. 2012 Feb;120(4):528-40
• All: 1 reference(s)