Hprt1^{tm2(Trp53RE-EGFP)Dpl}
Targeted Allele Detail

Summary

• Symbol: Hprt1^{tm2(Trp53RE-EGFP)Dpl}
• Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, David P Lane
• MGI ID: MGI:5315857
• Synonyms: Pumap53RE-EGFP
• Gene: Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
• Alliance: Hprt1^{tm2(Trp53RE-EGFP)Dpl} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182031
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutation: Insertion The Trp53 response element from Bbc3 and a delta fos minimal promoter drives expression of EGFP. (J:182031)

Generation of the Hprt1^tm2(Trp53RE-EGFP)Dpl allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hprt1 Mutation: 1280 strains or lines available

References

• Original: J:182031 Goh AM, et al., Using targeted transgenic reporter mice to study promoter-specific p53 transcriptional activity. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1685-90
• All: 1 reference(s)