Tg(CAG-GLVP)#Cath
Transgene Detail

Summary

• Symbol: Tg(CAG-GLVP)#Cath
• Name: transgene insertion, Charles A Thornton
• MGI ID: MGI:5314751
• Synonyms: CAG-GLVP
• Transgene: Tg(CAG-GLVP)#Cath Location: unknown
• Alliance: Tg(CAG-GLVP)#Cath page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene consists of the GLVPc914 cDNA (the GLVP transactivator) under the control of the CMV early enhancer/chicken beta actin (CAG) promoter. The GLVP portion consists of a mutated human progesterone receptor ligand binding domain fused to the yeast GAL4 DNA binding domain and the HSV VP16 transcriptional activation domain. Three lines were made, however the pound symbol (#) is used when line is not specified and/or lines are pooled. (J:178541)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:178541 Mankodi A, et al., Progressive myopathy in an inducible mouse model of oculopharyngeal muscular dystrophy. Neurobiol Dis. 2012 Jan;45(1):539-46
• All: 1 reference(s)