Hesx1tm4.1Jpmb
Targeted Allele Detail
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Symbol: |
Hesx1tm4.1Jpmb |
Name: |
homeobox gene expressed in ES cells; targeted mutation 4.1, Juan Pedro Martinez Barbera |
MGI ID: |
MGI:5314527 |
Synonyms: |
Hesx1eGFP |
Gene: |
Hesx1 Location: Chr14:26716373-26724286 bp, + strand Genetic Position: Chr14, 16.09 cM, cytoband A3-B
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Alliance: |
Hesx1tm4.1Jpmb page
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Germline Transmission: |
Earliest citation of germline transmission:
J:181005
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Parent Cell Line: |
CCE/EK.CCE (ES Cell)
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Strain of Origin: |
129S/SvEv-Gpi1c
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exons 1 through 3 were replaced with a reporter cassette that contained a floxed EGFP and 5x polyadenylation sites, DTA and FRT-flanked neo cassette. Flp-mediated recombination removed the neo cassette.
(J:181005)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Hesx1 Mutation: |
14 strains or lines available
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Original: |
J:181005 Andoniadou CL, et al., HESX1- and TCF3-mediated repression of Wnt/beta-catenin targets is required for normal development of the anterior forebrain. Development. 2011 Nov;138(22):4931-42 |
All: |
1 reference(s) |
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