b2b370.1Clo
Chemically induced Allele Detail
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Symbol: |
b2b370.1Clo |
Name: |
Mutant line 370, subline 1; Bench to Bassinet Program (B2B/CVDC), mutation 370, subline 1 Cecilia Lo |
MGI ID: |
MGI:5313523 |
Gene: |
b2b370.1Clo Location: unknown
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Alliance: |
b2b370.1Clo page
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Craniofacial abnormalities including proboscis, lack of mouth and lower jaw.
Show the 8 phenotype image(s) involving this allele.
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Strain of Origin: |
C57BL/6J
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Project Collection: |
B2B/CvDC
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Allele Type: |
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Chemically induced (ENU) |
Mutation: |
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Undefined
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Mutation details: This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. It is a subline of b2b370Clo.
Additional
incidental mutations
were detected in sequencing for the causative mutation,
b2b370.1Clo, and may be present in stocks carrying this mutation.
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Carrying any b2b370.1Clo Mutation: |
1 strain or line available
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This mutation was derived from the parent line b2b370Clo.
Summative Diagnosis:
Cardiovascular defects: Right aortic arch (RAA), hypoplastic ascending aorta and brachiocephalic arteries. Non-cardiac defects: Noncardiac defects: Craniofacial defects - proboscis, micrognathia, no oral cavity opening (no mouth), holosproencephaly
Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) ( http://www.ipccc.net/).
Fyler Code ID |
Code Description |
2600 |
Systemic artery anomaly |
2700 |
Abnormal aortic arch |
2721 |
Right aortic arch with abnormal branching pattern |
3804 |
Congenital heart disease |
4163 |
Micrognathia |
4874 |
Mouth malformation |
4907 |
Non-cardiac thoracic abnormality |
Original: |
J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12; |
All: |
2 reference(s) |
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