Gt(ROSA)26Sor^{tm2(CAG-tdTomato)Fawa}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(CAG-tdTomato)Fawa}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Fan Wang
• MGI ID: MGI:5305341
• Synonyms: Rosa26-lox-stop-lox-tdTomato
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(CAG-tdTomato)Fawa} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180047
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A construct containing the chicken beta-actin promoter (CAG) with a loxP-STOP-loxP cassette preceding a farnesylated tdTomato sequence was inserted into intron 1 of the Gt(ROSA)26Sor locus via homologous recombination. Cre-mediated recombination of this allele results in expression of the tdTomato reporter driven by the CAG promoter. (J:180047)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:180047 Rock JR, et al., Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):E1475-83
• All: 16 reference(s)