Tg(Chx10-cre)5Tfur
Transgene Detail

Summary

• Symbol: Tg(Chx10-cre)5Tfur
• Name: transgene insertion 5, Takahisa Furukawa
• MGI ID: MGI:5302217
• Synonyms: Chx10-Cre, Tg(Chx10-cre)1Tfur
• Transgene: Tg(Chx10-cre)5Tfur Location: unknown
• Alliance: Tg(Chx10-cre)5Tfur page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Chx10-cre)5Tfur expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Vsx2 (MGI:88401)

• Mutation details: A BAC containing the Chx10 locus was modified by insertion of a cre recombinase-polyA sequence into the first exon of Chx10. Line 5 was generated. (J:177908)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Vsx2 (mouse) Summary of all recombinase alleles driven by Vsx2. Comparative matrix view of recombinase activities Alliance mouse Vsx2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:177908 Muranishi Y, et al., An Essential Role for RAX Homeoprotein and NOTCH-HES Signaling in Otx2 Expression in Embryonic Retinal Photoreceptor Cell Fate Determination. J Neurosci. 2011 Nov 16;31(46):16792-807
• All: 12 reference(s)