Tg(KRT5-E2F3)3.2Dgj
Transgene Detail

Summary

• Symbol: Tg(KRT5-E2F3)3.2Dgj
• Name: transgene insertion 3.2, David G Johnson
• MGI ID: MGI:5302003
• Synonyms: K5 E2F3
• Transgene: Tg(KRT5-E2F3)3.2Dgj Location: unknown
• Alliance: Tg(KRT5-E2F3)3.2Dgj page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT5-E2F3)3.2Dgj expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  E2F3 (1871)

  E2f3	(MGI:1096340)

• Tg(KRT5-E2F3)3.2Dgj expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  cattle	KRT5 (281268)

• Mutation details: The transgenic vector expressed full-length human E2F3 (E2F3A) cDNA driven by a bovine KRT5 promoter. Line 3.2 was established. (J:107082)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:107082 Paulson QX, et al., E2F3a stimulates proliferation, p53-independent apoptosis and carcinogenesis in a transgenic mouse model. Cell Cycle. 2006 Jan;5(2):184-90
• All: 2 reference(s)