Tg(tetO-GCaMP2)12IRyu
Transgene Detail
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Symbol: |
Tg(tetO-GCaMP2)12IRyu |
Name: |
transgene insertion 12I, Ron Yu |
MGI ID: |
MGI:5301601 |
Transgene: |
Tg(tetO-GCaMP2)12IRyu Location: unknown
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Alliance: |
Tg(tetO-GCaMP2)12IRyu page
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Strain of Origin: |
(CBA x FVB)F1
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Transgene Type: |
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Transgenic (Inducible, Reporter) |
Inducer: |
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doxycycline/tetracycline |
Mutation: |
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Insertion
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Mutation details: This transgene contains a calcium-sensing molecule, GCaMP2, under the transcriptional control of the tetracycline-responsive promoter element (tetO). GCaMP2 consists of, from 5' to 3', a 13-residue peptide of myosin light chain kinase (M13), a circularly permutated eGFP interrupted at residue 145, calmodulin (CaM), and a polyA recognition sequence. Mutations resulting in increased brightness (D180Y and V93I), thermal stability (V163A, and S175G), and GFP dimerization prevention (A206K) were introduced.
(J:157448, J:179273)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:179273 Yu R, Direct Data Submission 2012/01/17. MGI Direct Data Submission. 2012; |
All: |
7 reference(s) |
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