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Tg(tetO-Stat5a*S710F,-luc)11651Kuw
Transgene Detail
Summary
Symbol: Tg(tetO-Stat5a*S710F,-luc)11651Kuw
Name: transgene insertion 11651, Kay-Uwe Wagner
MGI ID: MGI:5300597
Synonyms: TetO-Stat5(S710F)Flag-IRES-luciferase
Transgene: Tg(tetO-Stat5a*S710F,-luc)11651Kuw  Location: unknown  
Alliance: Tg(tetO-Stat5a*S710F,-luc)11651Kuw page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence, Reporter)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsThe tetracycline operator drives inducible expression of the FLAG-tagged mouse cDNA with a point mutation that results in an amino acid substitution of phenylalanine for serine at position 710 (S710F) and an IRES-luciferase reporter. Lines 11651 and 11676 were generated. (J:162571)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:162571 Creamer BA, et al., Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1. Mol Cell Biol. 2010 Jun;30(12):2957-70
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory