Tg(Myh6-Akt1*K179M)1Siz
Transgene Detail

Summary

• Symbol: Tg(Myh6-Akt1*K179M)1Siz
• Name: transgene insertion 1, Seigo Izumo
• MGI ID: MGI:5300569
• Synonyms: kdAkt
• Transgene: Tg(Myh6-Akt1*K179M)1Siz Location: unknown
• Alliance: Tg(Myh6-Akt1*K179M)1Siz page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Akt1*K179M)1Siz expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Akt1 (MGI:87986)	Transgene codes for a protein with a lysine to methionine mutation.

• Mutation details: This transgene expresses a kinase deficient mouse Akt1, in which the critical ATP binding site was mutated (K179M), under the control of the mouse alpha-myosin heavy chain. (J:75780)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:75780 Shioi T, et al., Akt/protein kinase B promotes organ growth in transgenic mice. Mol Cell Biol. 2002 Apr;22(8):2799-809
• All: 3 reference(s)