Tg(MMTV-tTA)25754Kuw
Transgene Detail
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| Symbol: |
Tg(MMTV-tTA)25754Kuw |
| Name: |
transgene insertion 25754, Kay-Uwe Wagner |
| MGI ID: |
MGI:5300554 |
| Synonyms: |
MMTV-tTA |
| Transgene: |
Tg(MMTV-tTA)25754Kuw Location: unknown Genetic Position: Chr8, Syntenic
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| Alliance: |
Tg(MMTV-tTA)25754Kuw page
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| Transgene Type: |
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Transgenic (Transactivator) |
| Mutation: |
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Insertion
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Mutation details: The mouse mammary gland tumor virus (MMTV) promoter drives mammary gland-specific expression of a tetracycline transactivator (tTA). Two lines were generated (25754 and 25755). Line 25754 integrated on chromosome 8 (chr8:12,485,790-12,564,686; mouse mm10), approximately 10kb upstream of the Spaca7 locus. Currently there are no genes annotated in the integration region. This analysis also identified the transgene includes an SV40 NLS and polyA signal.
(J:178842)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:178842 Zhang Q, et al., Cyclin D3 Compensates for the Loss of Cyclin D1 during ErbB2-Induced Mammary Tumor Initiation and Progression. Cancer Res. 2011 Dec 15;71(24):7513-24 |
| All: |
5 reference(s) |
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Analysis Tools
