Nkx3-2^tm2.1Tlu
Targeted Allele Detail

Summary

• Symbol: Nkx3-2^tm2.1Tlu
• Name: NK3 homeobox 2; targeted mutation 2.1, Thomas Lufkin
• MGI ID: MGI:5300545
• Synonyms: FLAG-Bapx1^FE
• Gene: Nkx3-2 Location: Chr5:41918826-41921563 bp, - strand Genetic Position: Chr5, 22.58 cM
• Alliance: Nkx3-2^tm2.1Tlu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178821
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A triple FLAG-tag was inserted at the translation initiation codon. An F2A-EGFP-FRT-Neo-FRT was inserted at the stop codon. Flp-mediated recombination removed the neo cassette. (J:178821)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nkx3-2 Mutation: 21 strains or lines available

References

• Original: J:178821 Chan HY, et al., Comparison of IRES and F2A-based locus-specific multicistronic expression in stable mouse lines. PLoS One. 2011;6(12):e28885
• All: 1 reference(s)