Scnn1gtm1e(EUCOMM)Wtsi
Targeted Allele Detail
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Symbol: |
Scnn1gtm1e(EUCOMM)Wtsi |
Name: |
sodium channel, nonvoltage-gated 1 gamma; targeted mutation 1e, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5299883 |
Gene: |
Scnn1g Location: Chr7:121333702-121367698 bp, + strand Genetic Position: Chr7, 65.07 cM
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Alliance: |
Scnn1gtm1e(EUCOMM)Wtsi page
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IMPC: |
Scnn1g gene page |
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Mutant Cell Lines: |
EPD0795_5_B01, EPD0795_5_C04, EPD0795_5_D01, EPD0795_5_F01 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: The L1L2_Bact_P cassette was inserted at position 121341022 of Chromosome 7 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:155845, J:173534)
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Original: |
J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010; |
All: |
3 reference(s) |
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