b2b191Clo
Chemically induced Allele Detail

Summary

• Symbol: b2b191Clo
• Name: Mutant line 191; Bench to Bassinet Program (B2B/CVDC), mutation 191 Cecilia Lo
• MGI ID: MGI:5297421
• Synonyms: Shizou (SHIN-TSO)
• Gene: b2b191Clo Location: unknown
• Alliance: b2b191Clo page

EFIC Summary

Show the 15 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any b2b191Clo Mutation: 0 strains or lines available

Notes

Summative Diagnosis:
Cardiovascular defects: Double outlet right ventricle (DORV),overriding aorta, ventricular septal defects (VSD), atrio-ventricular septal defects (AVSD), pulmonary stenosis (outflow track and main-pulmonary artery), right aortic arch (RAA), and left coronary artery fistula.
Non-cardiovascular defect: Cleft palate

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
0606	DORV + AVSD (AV canal)
1310	Ventricular septal defect, membranous
1320	Ventricular septal defect, muscular
2230	Coronary fistula (arterio-venous or arterio-cameral)
2721	Right aortic arch with abnormal branching pattern
3804	Congenital heart disease

References

• Original: J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12
• All: 2 reference(s)