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Targeted Allele Detail
Symbol: Snap25tm1Mtaka
Name: synaptosomal-associated protein 25; targeted mutation 1, Masami Takahashi
MGI ID: MGI:5297219
Synonyms: Snap25S187A
Gene: Snap25  Location: Chr2:136555373-136624348 bp, + strand  Genetic Position: Chr2, 67.56 cM
Alliance: Snap25tm1Mtaka page
Abnormal locomotor activity in open field in Snap25tm1Mtaka/Snap25tm1Mtaka mice

Show the 3 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:177870
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Not Specified)
Mutations:    Insertion, Nucleotide substitutions
Mutation detailsA minigene containing a cDNA with nucleotide substitution(s) that results in the amino acid substitution of alanine for serine at position 187 (S187A) and a neo cassette were inserted into exon 7. (J:177870)
Generation of the Snap25tm1Mtaka allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Snap25 Mutation:  26 strains or lines available
Original:  J:177870 Kataoka M, et al., A single amino acid mutation in SNAP-25 induces anxiety-related behavior in mouse. PLoS One. 2011;6(9):e25158
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.23
The Jackson Laboratory