Vipr1^tm1Msod
Targeted Allele Detail

Summary

• Symbol: Vipr1^tm1Msod
• Name: vasoactive intestinal peptide receptor 1; targeted mutation 1, Mary Sue O'Dorisio
• MGI ID: MGI:5296326
• Gene: Vipr1 Location: Chr9:121471782-121502020 bp, + strand Genetic Position: Chr9, 72.5 cM
• Alliance: Vipr1^tm1Msod page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177616
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4 through 6 were replaced with a neo cassette. The absence of transcript with exon 4 to 5 was confirmed by RT-PCR on intestinal and brain extracts. (J:177616)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vipr1 Mutation: 41 strains or lines available

References

• Original: J:177616 Fabricius D, et al., Characterization of intestinal and pancreatic dysfunction in VPAC1-null mutant mouse. Pancreas. 2011 Aug;40(6):861-71
• All: 3 reference(s)