Usp2^tm1Ssw
Targeted Allele Detail

Summary

• Symbol: Usp2^tm1Ssw
• Name: ubiquitin specific peptidase 2; targeted mutation 1, Simon S Wing
• MGI ID: MGI:5295261
• Gene: Usp2 Location: Chr9:43978318-44006924 bp, + strand Genetic Position: Chr9, 24.53 cM, cytoband B
• Alliance: Usp2^tm1Ssw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176705
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT flanked neomycin/kanamycin selection cassette and loxP site were inserted upstream of exon 4 and a loxP site was inserted downstream of exon 6 via homologous recombination. (J:176705)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp2 Mutation: 36 strains or lines available

References

• Original: J:176705 Bedard N, et al., Mice lacking the USP2 deubiquitinating enzyme have severe male subfertility associated with defects in fertilization and sperm motility. Biol Reprod. 2011 Sep;85(3):594-604
• All: 2 reference(s)