Lmx1a^tm1Aman
Targeted Allele Detail

Summary

• Symbol: Lmx1a^tm1Aman
• Name: LIM homeobox transcription factor 1 alpha; targeted mutation 1, Ahmed Mansouri
• MGI ID: MGI:5294386
• Gene: Lmx1a Location: Chr1:167516806-167676310 bp, + strand Genetic Position: Chr1, 75.08 cM
• Alliance: Lmx1a^tm1Aman page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171625
• Parent Cell Line: MPI-II (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The endogenous ATG start codon was replaced with EGFP coding sequence followed by a PGK-neomycin cassette. (J:171625)

Expression

In Mice Carrying this Mutation:

32 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lmx1a Mutation: 21 strains or lines available

References

• Original: J:171625 Griesel G, et al., Generation of knockout mice expressing a GFP-reporter under the control of the Lmx1a locus. Gene Expr Patterns. 2011 Jun-Jul;11(5-6):345-8
• All: 2 reference(s)