Angptl8^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Angptl8^{tm1(KOMP)Vlcg}
• Name: angiopoietin-like 8; targeted mutation 1, Velocigene
• MGI ID: MGI:5292942
• Synonyms: Angptl8^-, Angptl8^hum
• Gene: Angptl8 Location: Chr9:21746806-21748643 bp, + strand Genetic Position: Chr9, 7.9 cM
• Alliance: Angptl8^{tm1(KOMP)Vlcg} page
• IMPC: Angptl8 gene page

Mutation origin

• Mutant Cell Lines: 18577A-B4, 18577A-B7, 18577A-H10
• Germline Transmission: Earliest citation of germline transmission: J:217262
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1632bp between positions 21746817-21748448 of Chromosome 9 (Build GRCm39). The deletion includes exon 1, 2, 3, and a small part of exon 4. (J:136110, J:217262)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Angptl8 Mutation: 15 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 5 reference(s)