About   Help   FAQ
Gt(ROSA)26Sortm1(ACTB-cre,-EGFP)Ics
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(ACTB-cre,-EGFP)Ics
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Mouse Clinical Institute
MGI ID: MGI:5285392
Synonyms: ROSA26Cre-GFP, Rosa26tm1(AC.cre2AeGFP)Ics, RosaCre-GFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(ACTB-cre,-EGFP)Ics page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:185484
Parent Cell Line:  BD10 (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(ACTB-cre,-EGFP)Ics expression driven by 1 gene
 
Mutation detailsA construct, which contains a beta actin promoter driving ubiquitous expression of cre and EGFP separated by a 2a peptide sequence, was inserted into the locus. (J:185484)
Generation of the Gt(ROSA)26Sortm1(ACTB-cre,-EGFP)Ics allele
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: ACTB (species not specified)
Summary of all recombinase alleles driven by ACTB.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  968 strains or lines available
References
Original:  J:185484 Birling MC, et al., Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background. Genesis. 2012 Jun;50(6):482-9
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
07/05/2024
MGI 6.24
The Jackson Laboratory