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Targeted Allele Detail
Symbol: Gt(ROSA)26Sortm1(ACTB-cre,-EGFP)Ics
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Mouse Clinical Institute
MGI ID: MGI:5285392
Synonyms: ROSA26Cre-GFP, Rosa26tm1(AC.cre2AeGFP)Ics, RosaCre-GFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(ACTB-cre,-EGFP)Ics page
Germline Transmission:  Earliest citation of germline transmission: J:185484
Parent Cell Line:  BD10 (ES Cell)
Strain of Origin:  C57BL/6NTac
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
Gt(ROSA)26Sortm1(ACTB-cre,-EGFP)Ics expression driven by 1 gene
Mutation detailsA construct, which contains a beta actin promoter driving ubiquitous expression of cre and EGFP separated by a 2a peptide sequence, was inserted into the locus. (J:185484)
Generation of the Gt(ROSA)26Sortm1(ACTB-cre,-EGFP)Ics allele
 Tissue activity of this recombinase allele
Driver: ACTB (species not specified)
Summary of all recombinase alleles driven by ACTB.

In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  968 strains or lines available
Original:  J:185484 Birling MC, et al., Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background. Genesis. 2012 Jun;50(6):482-9
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
The Jackson Laboratory