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Trpv1tm2Bbm
Targeted Allele Detail
Summary
Symbol: Trpv1tm2Bbm
Name: transient receptor potential cation channel, subfamily V, member 1; targeted mutation 2, Allan Basbaum
MGI ID: MGI:5141471
Synonyms: TRPV1PLAP-nlacZ
Gene: Trpv1  Location: Chr11:73125118-73152068 bp, + strand  Genetic Position: Chr11, 45.25 cM, cytoband B3
Alliance: Trpv1tm2Bbm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174728
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting vector containing IRES-PLAP (alkaline phosphatase, placental)-IRES-nlacZ (nuclear lacZ) sequence was inserted immediately 3' of the stop codon of the gene. The endogenous coding sequence is not disrupted. (J:174728)
Expression
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trpv1 Mutation:  59 strains or lines available
References
Original:  J:174728 Cavanaugh DJ, et al., Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J Neurosci. 2011 Mar 30;31(13):5067-77
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory