Pex5l^tm1Chet
Targeted Allele Detail

Summary

• Symbol: Pex5l^tm1Chet
• Name: peroxisomal biogenesis factor 5-like; targeted mutation 1, Dane Chetkovich
• MGI ID: MGI:5139911
• Synonyms: Pex5l^Fneo
• Gene: Pex5l Location: Chr3:33003557-33197396 bp, - strand Genetic Position: Chr3, 15.94 cM, cytoband B
• Alliance: Pex5l^tm1Chet page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173355
• Parent Cell Line: PRX-B6N (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 6. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 7. (J:173355)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pex5l Mutation: 39 strains or lines available

References

• Original: J:173355 Lewis AS, et al., Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice. J Neurosci. 2011 May 18;31(20):7424-40
• All: 1 reference(s)