Mgl2/Clec10a^tm1.2Cfg
Targeted Allele Detail

Summary

• Symbol: Mgl2/Clec10a^tm1.2Cfg
• Name: macrophage galactose N-acetyl-galactosamine specific lectin 2; targeted mutation 1.2, Consortium for Functional Glycomics
• MGI ID: MGI:5052343
• Gene: Mgl2 Location: Chr11:70021155-70028376 bp, + strand Genetic Position: Chr11, 42.99 cM
• Alliance: Mgl2/Clec10a^tm1.2Cfg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked selection vector containing a neomycin resistance gene and a single 5' loxP site was inserted upstream of exon 2 of the Mgl2 gene and a second loxP site was inserted downstream of exon 10 of the Clec10a gene. The selection cassette was subsequently removed from properly targeted mice by crossing to transgenic mice carrying Tg(ACTFLPe)9205Dym. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mgl2 Mutation: 25 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)