Pomgnt1^tm1.1Cfg
Targeted Allele Detail

Summary

• Symbol: Pomgnt1^tm1.1Cfg
• Name: protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase; targeted mutation 1.1, Consortium for Functional Glycomics
• MGI ID: MGI:5052171
• Gene: Pomgnt1 Location: Chr4:116007700-116017041 bp, + strand Genetic Position: Chr4, 53.1 cM, cytoband C7
• Alliance: Pomgnt1^tm1.1Cfg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP-flanked PGKneo cassette site was inserted upstream of exon 7 and a third loxP site was inserted downstream of exon 16. Cre-mediated recombination removed the neo cassette. Exons 7 through 16 were subsequently removed from properly targeted mice by crossing to transgenic mice carrying Tg(EIIa-cre)C5379Lmgd. (J:94077)

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pomgnt1 Mutation: 63 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 3 reference(s)