Gt(ROSA)26Sor^tm1Sia
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1Sia
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Shinichi Aizawa
• MGI ID: MGI:5052151
• Synonyms: Gt(ROSA)26Sor^{tm1(HIST1H2BB-mCherry/EGFP)Sia}, R26R-RG
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173653
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A vector, which contains (5' to 3') a splice acceptor, floxed neo/stop cassette, chromatin-associated human HIST1H2BB, mCherry, self-cleavage 2A peptide sequence, endoplasmic reticulum signal peptide sequence, EGFP, and GPI anchor sequence, was inserted into the locus. (J:173653)

Generation of the Gt(ROSA)26Sor^tm1Sia and Gt(ROSA)26Sor^tm1.1Sia alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:173653 Shioi G, et al., A mouse reporter line to conditionally mark nuclei and cell membranes for in vivo live-imaging. Genesis. 2011 Jul;49(7):570-8
• All: 2 reference(s)