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Cdk4wnch
Chemically induced Allele Detail
Summary
Symbol: Cdk4wnch
Name: cyclin dependent kinase 4; wanchi
MGI ID: MGI:5009264
Synonyms: ENU8B6:053
Gene: Cdk4  Location: Chr10:126899404-126903157 bp, + strand  Genetic Position: Chr10, 74.5 cM, cytoband D3
Alliance: Cdk4wnch page
Mutation
origin
Strain of Origin:  C57BL/6JAnu
Project Collection: APF ENU Mutagenesis
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a T to A transversion at position 1152 (ENSMUST00000006911) in exon 8 that results in the amino acid substitution of arginine for the stop codon at position 304 (X304R). The predicted peptide has an additional 40 amino acids added to the end before another STOP. (J:104190)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cdk4 Mutation:  57 strains or lines available
References
Original:  J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory