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L1td1tm1Yam
Targeted Allele Detail
Summary
Symbol: L1td1tm1Yam
Name: LINE-1 type transposase domain containing 1; targeted mutation 1, Shinya Yamanaka
MGI ID: MGI:5008637
Synonyms: ECAT11EGFP
Gene: L1td1  Location: Chr4:98614991-98626723 bp, + strand  Genetic Position: Chr4, 45.6 cM
Alliance: L1td1tm1Yam page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:172565
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region was replaced with EGFP, IRES, and a puro cassette. The absence of protein expression was confirmed by western blot analysis on ES cell extracts. (J:172565)
Generation of the L1td1tm1Yam allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any L1td1 Mutation:  78 strains or lines available
References
Original:  J:172565 Iwabuchi KA, et al., ECAT11/L1td1 Is Enriched in ESCs and Rapidly Activated During iPSCGeneration, but It Is Dispensable for the Maintenance and Induction of Pluripotency. PLoS One. 2011;6(5):e20461
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory