Csrp1^tm1Mbk
Targeted Allele Detail

Summary

• Symbol: Csrp1^tm1Mbk
• Name: cysteine and glycine-rich protein 1; targeted mutation 1, Mary C Beckerle
• MGI ID: MGI:5007641
• Gene: Csrp1 Location: Chr1:135647799-135679970 bp, + strand Genetic Position: Chr1, 59.23 cM
• Alliance: Csrp1^tm1Mbk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:172149
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 4 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on lung and uterus extracts. (J:172149)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Csrp1 Mutation: 19 strains or lines available

References

• Original: J:172149 Lilly B, et al., Loss of the serum response factor cofactor, cysteine-rich protein 1, attenuates neointima formation in the mouse. Arterioscler Thromb Vasc Biol. 2010 Apr;30(4):694-701
• All: 1 reference(s)