Minar2tm1e(KOMP)Wtsi
Targeted Allele Detail
|
Symbol: |
Minar2tm1e(KOMP)Wtsi |
Name: |
membrane integral NOTCH2 associated receptor 2; targeted mutation 1e, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5006750 |
Gene: |
Minar2 Location: Chr18:59195320-59210034 bp, + strand Genetic Position: Chr18, 33.9 cM
|
IMPC: |
Minar2 gene page |
|
Mutant Cell Lines: |
EPD0770_5_A07, EPD0770_5_D06 |
Germline Transmission: |
Unknown
|
Parent Cell Line: |
JM8A3.N1 (ES Cell)
|
Strain of Origin: |
C57BL/6N-Atm1Brd
|
Project Collection: |
KOMP-CSD
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutation: |
|
Insertion
Vector: L1L2_Bact_P
|
|
|
Mutation details: The L1L2_Bact_P cassette was inserted at position 59204783 of Chromosome 18 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:148605, J:173534)
|
|
|
|
Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
All: |
2 reference(s) |
|