Il17a^tm1.1Flv
Targeted Allele Detail

Summary

• Symbol: Il17a^tm1.1Flv
• Name: interleukin 17A; targeted mutation 1.1, Richard A Flavell
• MGI ID: MGI:5006665
• Synonyms: IL-17A eGFP
• Gene: Il17a Location: Chr1:20801129-20804720 bp, + strand Genetic Position: Chr1, 6.45 cM, cytoband A
• Alliance: Il17a^tm1.1Flv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171598
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-eGFP-neo cassette was inserted downstream of the translation stop codon. Cre-mediated recombination removed the neo cassette. (J:171598)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il17a Mutation: 24 strains or lines available

References

• Original: J:171598 Huber S, et al., Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3(-) and Foxp3(+) Regulatory CD4(+) T Cells in an Interleukin-10-Dependent Manner. Immunity. 2011 Apr 22;34(4):554-65
• All: 27 reference(s)