Tg(Myh6/tetO-Gata6)2Jmol
Transgene Detail

Summary

• Symbol: Tg(Myh6/tetO-Gata6)2Jmol
• Name: transgene insertion 2, Jeffery Molkentin
• MGI ID: MGI:5002485
• Transgene: Tg(Myh6/tetO-Gata6)2Jmol Location: unknown
• Alliance: Tg(Myh6/tetO-Gata6)2Jmol page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(Myh6/tetO-Gata6)2Jmol expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Gata6 (MGI:107516)

• Mutation details: These Gata6 transgenic mice contains the GATA binding protein 6 (Gata6) sequence regulated by a tetracycline operator (tetO), driven by myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6 or alpha-MHC) promoter/enhancer elements. Three lines were generated. (J:171966)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:171966 van Berlo JH, et al., The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circ Res. 2010 Oct 15;107(8):1032-40
• All: 2 reference(s)