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Targeted Allele Detail
Symbol: Roratm1(cre)Ddmo
Name: RAR-related orphan receptor alpha; targeted mutation 1, Dennis D M O'Leary
MGI ID: MGI:5000017
Synonyms: RORalphaCre
Gene: Rora  Location: Chr9:68561068-69295528 bp, + strand  Genetic Position: Chr9, 37.45 cM
Alliance: Roratm1(cre)Ddmo page
Germline Transmission:  Earliest citation of germline transmission: J:171771
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
Roratm1(cre)Ddmo expression driven by 1 gene
Mutation detailsAn IRES/cre/FRT/neo/FRT expression cassette was inserted into the 3' noncoding region of the Rora gene. Cre expression is similar to endogenous expression. (J:171771, J:199176)
 Tissue activity of this recombinase allele
Driver: Rora (mouse)
Summary of all recombinase alleles driven by Rora.

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rora Mutation:  41 strains or lines available
Original:  J:171771 Wu CS, et al., Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci. 2010 Sep;32(5):693-706
All:  23 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
The Jackson Laboratory