Gnl3^{Gt(S4-4B1)Sor}
Gene trapped Allele Detail

Summary

• Symbol: Gnl3^{Gt(S4-4B1)Sor}
• Name: guanine nucleotide binding protein nucleolar 3; gene trap S4-4B1, Philippe Soriano
• MGI ID: MGI:4974804
• Synonyms: Ns^-, Ns^betageo
• Gene: Gnl3 Location: Chr14:30734390-30741088 bp, - strand Genetic Position: Chr14, 19.09 cM
• Alliance: Gnl3^{Gt(S4-4B1)Sor} page

Failure of Gnl3^{Gt(S4-4B1)Sor}/Gnl3^{Gt(S4-4B1)Sor} embryos to develop from compacted morulae to blastocysts

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: S4-4B1
• Germline Transmission: Earliest citation of germline transmission: J:185271
• Parent Cell Line: AK7.1 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: ROSAFARY
• Mutation details: The gene trap vector inserted into intron 1. Q-PCR confirmed the absence of transcript expression in E2.5 embryos. (J:185271)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  FHCRC-GT-S4-4B1	CG465947 ; (MGI Seq Detail)	3' RACE	Chr14:30739076-30739822 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  163 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Gnl3^{Gt(S4-4B1)Sor} allele

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gnl3 Mutation: 58 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)