Clock^tm1Jt
Targeted Allele Detail

Summary

• Symbol: Clock^tm1Jt
• Name: clock circadian regulator; targeted mutation 1, Joseph S Takahashi
• MGI ID: MGI:4950926
• Synonyms: 2xstopClock
• Gene: Clock Location: Chr5:76357715-76452639 bp, - strand Genetic Position: Chr5, 40.63 cM
• Alliance: Clock^tm1Jt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2 x C57BL/6Brd-Tyr^c-Brd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A cassette containing loxP-stop-tetO-loxP was inserted at the 5' end of the Clock gene, proximal to exon 4 where the translation start site is located. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Clock Mutation: 101 strains or lines available

Notes

ES cell = ER3.4 (129S7/SvEvBrd-Hprt^b-m2 x C57BL/6Brd-Tyr^c-Brd)

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)